Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252375 | 0.85 | CYP2C8 (0.31) | — | |
| SCHEMBL24252406 | 0.76 | CYP2D6 (0.37) | — | |
| SCHEMBL24252213 | 0.76 | ALDH1A1 (0.33) | ALDH1A1THRBMAPK1POLB | |
| SCHEMBL24252215 | 0.75 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL24252373 | 0.74 | HDAC4 (0.33) | ALDH1A1MAPK1PRMT5WDR77 | |
| SCHEMBL24252217 | 0.73 | — | — | |
| SCHEMBL24252374 | 0.68 | ROCK2 (0.32) | PRMT5WDR77 | |
| SCHEMBL24252370 | 0.67 | ROCK2 (0.34) | PRMT5WDR77 | |
| SCHEMBL24252229 | 0.66 | LRRK2 (0.35) | — | |
| SCHEMBL8871735 | 0.66 | ALDH1A1 (0.38) | ALDH1A1THRBMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |