Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252214 | 0.78 | — | — | |
| SCHEMBL24252376 | 0.73 | CLK4 (0.31) | — | |
| SCHEMBL24252371 | 0.73 | — | — | |
| SCHEMBL24252373 | 0.70 | HDAC4 (0.33) | ALDH1A1TP53MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL24252409 | 0.70 | CCNT1 (0.33) | — | |
| SCHEMBL24252378 | 0.69 | LMNA (0.35) | MAPT | |
| SCHEMBL24252213 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL24252377 | 0.68 | HRH3 (0.35) | MAPT | |
| SCHEMBL18748183 | 0.68 | KDM4E (0.37) | ALDH1A1TP53MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL24252219 | 0.67 | PRKDC (0.33) | ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196474-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |