Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252377 | 0.70 | HRH3 (0.35) | HRH3 | |
| SCHEMBL24252378 | 0.68 | LMNA (0.35) | HRH3 | |
| SCHEMBL24252219 | 0.57 | PRKDC (0.33) | — | |
| SCHEMBL24252525 | 0.56 | CYP1A2 (0.31) | — | |
| SCHEMBL22568592 | 0.53 | PKM (0.35) | — | |
| SCHEMBL15055455 | 0.52 | — | — | |
| SCHEMBL1928132 | 0.52 | KDM4E (0.58) | — | |
| SCHEMBL139049 | 0.52 | KDM4E (0.58) | — | |
| SCHEMBL2951425 | 0.52 | KDM4E (0.58) | — | |
| SCHEMBL17210337 | 0.51 | CNR2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |