Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252378 | 0.88 | LMNA (0.35) | LMNAMAPT | |
| SCHEMBL24252377 | 0.87 | HRH3 (0.35) | LMNAMAPTKDM4E | |
| SCHEMBL24252413 | 0.80 | GSK3B (0.43) | MAPTGSK3BCYP1A2 | |
| SCHEMBL24252229 | 0.77 | LRRK2 (0.35) | GSK3BPIM1 | |
| SCHEMBL24252525 | 0.72 | CYP1A2 (0.31) | PRKDCL3MBTL1CYP1A2CYP2C9GRM5 | |
| SCHEMBL24252214 | 0.69 | — | — | |
| SCHEMBL24252414 | 0.68 | GSK3B (0.38) | GSK3BCYP1A2 | |
| SCHEMBL24252372 | 0.67 | ALDH1A1 (0.33) | MAPTMAPK1ALDH1A1 | |
| SCHEMBL24252371 | 0.64 | — | — | |
| SCHEMBL24252376 | 0.64 | CLK4 (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196474-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |