Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252377 | 0.98 | HRH3 (0.35) | LMNAMAPTHRH3 | |
| SCHEMBL24252219 | 0.88 | PRKDC (0.33) | LMNAMAPT | |
| SCHEMBL24252414 | 0.79 | GSK3B (0.38) | — | |
| SCHEMBL24252407 | 0.77 | GSK3B (0.40) | — | |
| SCHEMBL24252374 | 0.76 | ROCK2 (0.32) | — | |
| SCHEMBL24252370 | 0.75 | ROCK2 (0.34) | — | |
| SCHEMBL24252214 | 0.71 | — | — | |
| SCHEMBL24252372 | 0.69 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL24252371 | 0.66 | — | — | |
| SCHEMBL24252376 | 0.66 | CLK4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |