Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 8/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252406 | 0.85 | CYP2D6 (0.37) | CYP2D6LMNAGAAGSK3B | |
| SCHEMBL24252410 | 0.78 | CCNT1 (0.33) | CYP2D6LMNAGAAGSK3BCCNT1 | |
| SCHEMBL24252409 | 0.77 | CCNT1 (0.33) | LMNAGAAGSK3BCCNT1CCNA2 | |
| SCHEMBL24252408 | 0.77 | GSK3B (0.33) | CYP2D6LMNAGAAGSK3BCCNT1 | |
| SCHEMBL24252375 | 0.73 | CYP2C8 (0.31) | — | |
| SCHEMBL24252376 | 0.73 | CLK4 (0.31) | — | |
| SCHEMBL24252414 | 0.70 | GSK3B (0.38) | CYP2D6GSK3BCYP1A2 | |
| SCHEMBL24252407 | 0.70 | GSK3B (0.40) | CYP2D6GSK3BCYP1A2 | |
| SCHEMBL24252413 | 0.69 | GSK3B (0.43) | CYP2D6GSK3BCYP1A2 | |
| SCHEMBL2814353 | 0.62 | HSP90AA1 (0.52) | CYP2D6LMNAGSK3BCCNT1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |