Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252407 | 0.99 | GSK3B (0.40) | GSK3BROCK2ROCK1CDC42BPBSCD | |
| SCHEMBL24252413 | 0.90 | GSK3B (0.43) | GSK3BCYP1A2CYP2D6CSNK1A1GSK3A | |
| SCHEMBL24252378 | 0.79 | LMNA (0.35) | — | |
| SCHEMBL24252377 | 0.77 | HRH3 (0.35) | — | |
| SCHEMBL24252374 | 0.76 | ROCK2 (0.32) | ROCK2ROCK1CDC42BPB | |
| SCHEMBL24252410 | 0.75 | CCNT1 (0.33) | GSK3BSCDSCD5CAMKK2CYP2D6 | |
| SCHEMBL24252370 | 0.75 | ROCK2 (0.34) | ROCK2ROCK1CDC42BPB | |
| SCHEMBL24252409 | 0.74 | CCNT1 (0.33) | GSK3BSCDSCD5CAMKK2CDC7 | |
| SCHEMBL24252408 | 0.70 | GSK3B (0.33) | GSK3BCYP2D6 | |
| SCHEMBL24252411 | 0.70 | CYP2D6 (0.33) | GSK3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |