Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252212 | 0.85 | CTDSP1 (0.33) | — | |
| SCHEMBL24252215 | 0.78 | PRMT5 (0.32) | — | |
| SCHEMBL24252373 | 0.77 | HDAC4 (0.33) | EGLN1 | |
| SCHEMBL24252217 | 0.77 | — | — | |
| SCHEMBL24252411 | 0.73 | CYP2D6 (0.33) | — | |
| SCHEMBL24252376 | 0.73 | CLK4 (0.31) | — | |
| SCHEMBL24252374 | 0.70 | ROCK2 (0.32) | — | |
| SCHEMBL24252370 | 0.70 | ROCK2 (0.34) | — | |
| SCHEMBL24252229 | 0.69 | LRRK2 (0.35) | — | |
| SCHEMBL1456807 | 0.62 | GOT1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |