Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254545 | 0.85 | SELL (0.45) | L3MBTL1LMNAKMT2AMEN1MAPT | |
| SCHEMBL24254523 | 0.83 | HPGD (0.59) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL26188046 | 0.80 | ALDH1A1 (0.58) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL24254575 | 0.80 | MAPT (0.53) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL24254539 | 0.74 | MAPT (0.53) | LMNAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL24254498 | 0.72 | ALDH1A1 (0.63) | LMNAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6785823 | 0.71 | HTT (0.57) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL2071340 | 0.71 | L3MBTL1 (0.81) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL6405857 | 0.70 | ALDH1A1 (0.73) | L3MBTL1LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL16098448 | 0.69 | ALDH1A1 (0.67) | L3MBTL1LMNAKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035804-A1 | SUBSTITUTED 3-AMINO-4-METHYLBENZENESULFONAMIDES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |