Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254523 | 0.89 | HPGD (0.59) | SELLSELPHPGDKMT2AMEN1 | |
| SCHEMBL24254578 | 0.85 | L3MBTL1 (0.57) | KMT2AMEN1POLBHTTL3MBTL1 | |
| SCHEMBL24254575 | 0.84 | MAPT (0.53) | KMT2AMEN1POLBHTTL3MBTL1 | |
| SCHEMBL24254539 | 0.78 | MAPT (0.53) | KMT2AMEN1HTTLMNAGAA | |
| SCHEMBL24254504 | 0.77 | ALDH1A1 (0.63) | KMT2APOLBL3MBTL1LMNAGAA | |
| SCHEMBL24254498 | 0.77 | ALDH1A1 (0.63) | SELLSELPKMT2AMEN1POLB | |
| SCHEMBL24254579 | 0.72 | MEN1 (0.57) | KMT2AMEN1POLBHTTL3MBTL1 | |
| SCHEMBL13388743 | 0.72 | L3MBTL1 (0.54) | HPGDKMT2AMEN1POLBHTT | |
| SCHEMBL24254515 | 0.71 | MAPT (0.48) | KMT2AMEN1POLBHTTL3MBTL1 | |
| SCHEMBL14227343 | 0.69 | ALDH1A1 (0.57) | SELLSELPPOLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035804-A1 | SUBSTITUTED 3-AMINO-4-METHYLBENZENESULFONAMIDES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |