Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254523 | 0.84 | HPGD (0.59) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL24254501 | 0.80 | CTSD (0.62) | MAPTMEN1KMT2AKCNQ2KDM4E | |
| SCHEMBL24254545 | 0.78 | SELL (0.45) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL24254575 | 0.78 | MAPT (0.53) | MAPTMEN1KMT2AKCNQ2KDM4E | |
| SCHEMBL24254498 | 0.75 | ALDH1A1 (0.63) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL24254578 | 0.74 | L3MBTL1 (0.57) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL26077917 | 0.72 | MEN1 (0.55) | MAPTMEN1KMT2AKCNQ2MAPK8 | |
| SCHEMBL13753606 | 0.71 | MEN1 (0.63) | MAPTMEN1KMT2AKCNQ2KDM4E | |
| SCHEMBL6850939 | 0.71 | MEN1 (0.67) | MAPTMEN1KMT2AKCNQ2KDM4E | |
| SCHEMBL1853620 | 0.70 | MEN1 (0.62) | MAPTMEN1KMT2AKCNQ2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035804-A1 | SUBSTITUTED 3-AMINO-4-METHYLBENZENESULFONAMIDES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |