Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24266787 | 0.90 | EYA3 (0.36) | KDRPREPCELA1THRATHRB | |
| SCHEMBL26211199 | 0.79 | CYP2C19 (0.41) | THRATHRBEYA3 | |
| SCHEMBL24267353 | 0.79 | ALDH1A1 (0.39) | EYA3 | |
| SCHEMBL25719653 | 0.78 | EYA3 (0.34) | KDRPREPCELA1THRATHRB | |
| SCHEMBL24103740 | 0.74 | CYP2C19 (0.32) | KDRPREPCELA1EYA3 | |
| SCHEMBL22072519 | 0.73 | TTR (0.46) | THRBEYA3 | |
| SCHEMBL22072522 | 0.70 | EYA3 (0.45) | THRBEYA3 | |
| SCHEMBL25815021 | 0.68 | EYA3 (0.60) | THRBEYA3 | |
| SCHEMBL24267018 | 0.68 | EYA3 (0.36) | EYA3 | |
| SCHEMBL25816065 | 0.68 | CYP2C19 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957629-A1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | Arthrosi Therapeutics, Inc. (US) | 2022-02-23 | — | — | EP | disclosed |