SCHEMBL2435152

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1135632	0.88	KDM4E (0.43)	KDM4EMAPTMEN1KMT2ANPBWR1
	SCHEMBL2434167	0.78	PIM1 (0.43)	KDM4EMAPTMEN1KMT2ANPBWR1
	SCHEMBL2430093	0.77	IDO1 (0.40)	KDM4EMAPTMEN1KMT2AALDH1A1
	SCHEMBL2427405	0.76	SIK1 (0.43)	MAPTMEN1KMT2AALDH1A1RAB9A
	SCHEMBL12160481	0.74	ABCB1 (0.43)	KDM4EMAPTMEN1KMT2AALDH1A1
	SCHEMBL2434369	0.74	HTR1A (0.40)	KDM4EMAPTKMT2AALDH1A1HSD17B10
	SCHEMBL2428272	0.74	ALDH1A1 (0.43)	KDM4EMAPTMEN1KMT2AALDH1A1
	SCHEMBL2432485	0.73	HTR1A (0.39)	KDM4EMAPTMEN1KMT2AALDH1A1
	SCHEMBL2429922	0.72	DCTPP1 (0.37)	KDM4EMAPTMEN1KMT2AALDH1A1
	SCHEMBL2432159	0.72	NPC1 (0.37)	KDM4EMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.