SCHEMBL2428272

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136221	0.89	MAPT (0.42)	ALDH1A1NPC1RAB9AHPGDMAPT
	SCHEMBL2434167	0.80	PIM1 (0.43)	ALDH1A1NPC1RAB9AHPGDMAPT
	SCHEMBL2427405	0.75	SIK1 (0.43)	ALDH1A1NPC1RAB9AMAPTMAOB
	SCHEMBL2435152	0.74	KDM4E (0.43)	ALDH1A1NPC1RAB9AHPGDMAPT
	SCHEMBL2430093	0.73	IDO1 (0.40)	ALDH1A1NPC1RAB9AHPGDMAPT
	SCHEMBL24860537	0.72	NPC1 (0.49)	ALDH1A1NPC1RAB9AHPGDMAPT
	SCHEMBL26011619	0.71	ESR1 (0.48)	ALDH1A1NPC1RAB9AHPGDMAPT
	SCHEMBL6173418	0.71	RAB9A (0.68)	ALDH1A1NPC1RAB9AHPGDMAPT
	SCHEMBL2434369	0.70	HTR1A (0.40)	ALDH1A1MAPTSMN1; SMN2TP53MAPK1
	SCHEMBL2432485	0.70	HTR1A (0.39)	ALDH1A1HPGDMAPTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.