Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286281 | 0.94 | PKM (0.49) | RORCPKMPKLRNR1H3NR1H2 | |
| SCHEMBL24286493 | 0.88 | RORC (0.63) | RORCPKMPKLR | |
| SCHEMBL24286427 | 0.87 | PKM (0.50) | RORCPKMPKLRNR1H3NR1H2 | |
| SCHEMBL24287119 | 0.86 | PKM (0.49) | RORCPKMPKLRNR1H3NR1H2 | |
| SCHEMBL24286273 | 0.85 | RORC (0.51) | RORCPKMPKLRNR1H3 | |
| SCHEMBL24286271 | 0.83 | PKM (0.54) | RORCPKMPKLRNR1H3NR1H2 | |
| SCHEMBL24286917 | 0.83 | PKM (0.46) | RORCPKMPKLRNR1H3NR1H2 | |
| SCHEMBL24286206 | 0.82 | RORC (0.64) | RORCPKMPKLRNR1H3 | |
| SCHEMBL24286648 | 0.81 | RORC (0.52) | RORCPKMPKLRHTT | |
| SCHEMBL24286225 | 0.81 | RORC (0.56) | RORCPKMPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307738-B1 | ARYL DIHYDRO-2H-BENZO[B][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORY AND THE TREATMENT OF DISEASE | UNIV MICHIGAN REGENTS (US) | 2022-04-20 | — | — | EP | disclosed |