Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.70 |
| ▸ | TERT | O14746 | 5/20 | 0.67 |
| ▸ | TOP1 | P11387 | 4/20 | 0.56 |
| ▸ | CYCS | P99999 | 3/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraphenylporphine Tetrasulfonic Acid SCHEMBL30826425 | 0.98 | ENPP2 (0.73) | ENPP2TERTTOP1CYCSABCG2 | |
| Water SCHEMBL8810288 | 0.98 | ENPP2 (0.68) | ENPP2TERTTOP1CYCSABCG2 | |
| SCHEMBL11527331 | 0.98 | ENPP2 (0.68) | ENPP2TERTTOP1CYCSABCG2 | |
| Zinc Ion SCHEMBL11569891 | 0.97 | ENPP2 (0.70) | ENPP2TERTTOP1CYCSABCG2 | |
| SCHEMBL5051415 | 0.97 | ENPP2 (0.70) | ENPP2TERTTOP1CYCSABCG2 | |
| SCHEMBL23706379 | 0.97 | ENPP2 (0.70) | ENPP2TERTTOP1CYCSABCG2 | |
| SCHEMBL6139711 | 0.97 | ENPP2 (0.70) | ENPP2TERTTOP1CYCSABCG2 | |
| SCHEMBL498417 | 0.97 | ENPP2 (0.70) | ENPP2TERTTOP1CYCSABCG2 | |
| SCHEMBL9267975 | 0.97 | TERT (0.71) | ENPP2TERTTOP1CYCSABCG2 | |
| SCHEMBL2334465 | 0.97 | ENPP2 (0.70) | ENPP2TERTTOP1CYCSABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140300857-A1 | OPHTHALMIC FILTER | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQU E) (FR) | 2014-10-09 | — | — | US | claimed |
| WO-2013084177-A1 | OPHTHALMIC FILTER | Essilor International (Compagnie Générale d'Optique) (FR) | 2013-06-13 | — | — | WO | claimed |
| EP-2602654-A1 | Ophthalmic filter | Essilor International (Compagnie Générale D'Optique) (FR) | 2013-06-12 | — | — | EP | claimed |
| EP-3371645-B1 | OPTICAL ARTICLE PROTECTING FROM BLUE LIGHT | ESSILOR INT (FR) | 2025-10-29 | — | — | EP | disclosed |
| EP-3807713-B1 | COLOR-BALANCED LENSES EXHIBITING REDUCED BLUE LIGHT TRANSMITTANCE | ESSILOR INT (FR) | 2025-08-06 | — | — | EP | disclosed |
| EP-3087312-B1 | HEAD-MOUNTED DISPLAY WITH FILTER FUNCTION | ESSILOR INT (FR) | 2024-09-11 | — | — | EP | disclosed |
| US-12019316-B2 | Color-balanced lenses exhibiting reduced blue light transmittance | ESSILOR INTERNATIONAL (FR) | 2024-06-25 | — | — | US | disclosed |
| EP-3296799-B1 | OPTICAL ARTICLE WITH BLUE CUT, HIGH UV CUT AND HIGH CLARITY | ESSILOR INT (FR) | 2024-05-22 | — | — | EP | disclosed |
| EP-2602655-B1 | Ophthalmic filter | ESSILOR INT (FR) | 2024-04-03 | — | — | EP | disclosed |
| CN-117003928-A | Composition for manufacturing an ophthalmic lens comprising an encapsulated light absorbing additive | 依视路国际公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-111433637-B | Composition for manufacturing an ophthalmic lens comprising an encapsulated light absorbing additive | 依视路国际公司 | 2023-11-03 | — | — | CN | disclosed |
| WO-2013084178-A1 | OPHTHALMIC FILTER | Essilor International (Compagnie Générale d'Optique) (FR) | 2013-06-13 | — | — | WO | disclosed |
| WO-2013084176-A1 | METHOD OF DETERMINING THE CONFIGURATION OF AN OPHTHALMIC FILTER | Essilor International (Compagnie Générale d'Optique) (FR) | 2013-06-13 | — | — | WO | disclosed |
| WO-2013084177-A1 | OPHTHALMIC FILTER | Essilor International (Compagnie Générale d'Optique) (FR) | 2013-06-13 | — | — | WO | disclosed |
| EP-2602653-A1 | Method of determining the configuration of an ophthalmic filter | Essilor International (Compagnie Générale D'Optique) (FR) | 2013-06-12 | — | — | EP | disclosed |
| EP-2602654-A1 | Ophthalmic filter | Essilor International (Compagnie Générale D'Optique) (FR) | 2013-06-12 | — | — | EP | disclosed |
| EP-2602655-A1 | Ophthalmic filter | Essilor International (Compagnie Générale D'Optique) (FR) | 2013-06-12 | — | — | EP | disclosed |
| EP-0501515-B1 | Optical recording material | TORAY INDUSTRIES (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5306599-A | Optical recording material | TORAY INDUSTRIES, INC. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0501515-A1 | Optical recording material | TORAY INDUSTRIES, INC. (JP) | 1992-09-02 | — | — | EP | disclosed |