SCHEMBL2430380

SCHEMBL2430380

COc1ccc(CSC(C)(C)CNCCNCC(C)(C)SCc2ccc(OC)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
IDO1 P14902 3/20 0.42
CHRM2 P08172 1/20 0.42
HTT P42858 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
POLB P06746 1/20 0.42
APP P05067 1/20 0.41
GAA P10253 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
HTR2A P28223 1/20 0.39
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8376336 0.93 MEN1 (0.47) MEN1KMT2AIDO1CHRM2HTT
SCHEMBL6604781 0.79 KMT2A (0.56) MEN1KMT2AHTTMAPTLMNA
SCHEMBL20435360 0.79 TAAR1 (0.50) MEN1KMT2AIDO1APPSMN1; SMN2
SCHEMBL20287965 0.79 ALDH1A1 (0.44) MEN1KMT2AIDO1HTTMAPT
SCHEMBL6578267 0.78 CYP3A4 (0.62) IDO1APPSMN1; SMN2ALDH1A1TP53
SCHEMBL7668721 0.77 IDO1 (0.52) IDO1APPSMN1; SMN2ALDH1A1TP53
SCHEMBL6575981 0.77 MEN1 (0.54) MEN1KMT2AIDO1HTTMAPT
SCHEMBL9112000 0.76 MEN1 (0.42) MEN1KMT2AIDO1HTTMAPT
SCHEMBL20425216 0.75 IDO1 (0.47) MEN1KMT2AIDO1HTTMAPT
SCHEMBL16589112 0.75 IDO1 (0.47) MEN1KMT2AIDO1APPSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319213-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS ABX ADVANCED BIOCHEMICAL COMPOUNDS – BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) 2025-10-16 US disclosed
EP-4529473-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS ABX Advanced Biochemical Compounds - Biomedizinische Forschungsreagenzien GmbH (DE) 2025-04-02 EP disclosed
WO-2023227535-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH (DE) 2023-11-30 WO disclosed
EP-4282438-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS ABX Advanced Biochemical Compounds GmbH (DE) 2023-11-29 EP disclosed
EP-1956013-B1 DIAGNOSTIC AND REMEDY FOR DISEASE CAUSED BY AMYLOID AGGREGATION AND/OR DEPOSITION FUJIFILM RI PHARMA CO LTD (JP) 2016-04-13 EP disclosed
EP-1956013-B1 DIAGNOSTIC AND REMEDY FOR DISEASE CAUSED BY AMYLOID AGGREGATION AND/OR DEPOSITION FUJIFILM RI PHARMA CO LTD (JP) 2016-04-13 EP disclosed
US-8022075-B2 Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition FUJIFILM RI PHARMA CO., LTD. (JP) 2011-09-20 US disclosed
US-8022075-B2 Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition FUJIFILM RI PHARMA CO., LTD. (JP) 2011-09-20 US disclosed
US-8022075-B2 Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition FUJIFILM RI PHARMA CO., LTD. (JP) 2011-09-20 US disclosed
US-20090162283-A1 DIAGNOSTIC AND REMEDY FOR DISEASE CAUSED BY AMYLOID AGGREGATION AND/OR DEPOSITION FUJIFILM RI PHARMA CO., LTD. (JP) 2009-06-25 US disclosed
US-5951964-A SCINTIGRAPHY; REAGENTS COMPRISED OF A MULTIPLICITY OF SPECIFIC-BINDING PEPTIDE MOIETIES HAVING AN AFFINITY FOR TARGETED SITES IN VIVO; POLYVALENT LINKAGES; KITS; DEEP-VENOUS THROMBI; CONTRAST; EFFICIENCY DIATIDE, INC. (US) 1999-09-14 US disclosed
EP-0637968-B1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATIDE INC (US) 1999-09-08 EP disclosed
US-5922303-A SCINTIGRAPHIC IMAGING AGENT DIATIDE, INC. (US) 1999-07-13 US disclosed
US-5849261-A Radiolabeled vasoactive intestinal peptides for diagnosis and therapy DIATIDE, INC. (US) 1998-12-15 US disclosed
US-5780007-A USED FOR RADIODIAGNOSIS DIATIDE, INC. (US) 1998-07-14 US disclosed
US-5776428-A Technetium-99m labeled peptides for imaging DIATIDE, INC. (US) 1998-07-07 US disclosed
US-5720934-A MEDICAL DIAGNOSIS DIATIDE, INC. (US) 1998-02-24 US disclosed
WO-1995025720-A1 PIPERIDYL-4-SUBSTITUTED THYROSINE DERIVATIVES AS SCINTIGRAPHIC IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOSIS DIATECH, INC. (US) 1995-09-28 WO disclosed
EP-0644778-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING. DIATECH INC (US) 1995-03-29 EP disclosed
WO-1993025244-A1 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING DIATECH, INC. (US) 1993-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319213-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS MARS1, MARS2, BCAT1 MEN1 81/4885KMT2A 590/4885IDO1 1647/4885
US-20090162283-A1 DIAGNOSTIC AND REMEDY FOR DISEASE CAUSED BY AMYLOID AGGREGATION AND/OR DEPOSITION APP, TTR, BACE1 MEN1 609/4885KMT2A 3062/4885IDO1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.