Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250850 | 0.82 | ACHE (0.54) | ALDH1A1ACHECNR1CNR2KMT2A | |
| SCHEMBL493687 | 0.82 | L3MBTL1 (0.51) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 | |
| SCHEMBL4261834 | 0.80 | L3MBTL3 (0.55) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 | |
| SCHEMBL493492 | 0.80 | TDP1 (0.52) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 | |
| SCHEMBL493703 | 0.79 | ALDH1A1 (0.46) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 | |
| SCHEMBL7467378 | 0.78 | L3MBTL3 (0.57) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 | |
| SCHEMBL16099153 | 0.77 | KMT2A (0.53) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 | |
| SCHEMBL5071336 | 0.76 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 | |
| SCHEMBL5071337 | 0.76 | CCR5 (0.46) | L3MBTL3L3MBTL1ALDH1A1OPRD1KMT2A | |
| SCHEMBL493765 | 0.76 | ALDH1A1 (0.63) | L3MBTL3L3MBTL1ALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024354-B1 | 1- [ (4- [BENZOYL (METHYL) AMINO]-3- (PHENYL) BUTYL]AZETIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS 1 | ALBIREO AB (SE) | 2011-09-21 | — | — | EP | claimed |