Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24309872 | 0.88 | CCNA2 (0.40) | KDRCCNA2CDK2CCNA1 | |
| SCHEMBL24309954 | 0.87 | HTR1D (0.36) | MAP4K1 | |
| SCHEMBL26809807 | 0.85 | HTR6 (0.35) | PLK1 | |
| SCHEMBL24309422 | 0.84 | MAP4K1 (0.33) | MAP4K1CCNA2CDK2CCNA1 | |
| SCHEMBL24310284 | 0.82 | MAP4K1 (0.37) | MAP4K1 | |
| SCHEMBL24310751 | 0.82 | MAP4K1 (0.34) | MAP4K1 | |
| SCHEMBL24309238 | 0.80 | MAP4K1 (0.36) | MAP4K1 | |
| SCHEMBL24310395 | 0.80 | HTR3A (0.39) | — | |
| SCHEMBL24310533 | 0.79 | MAP4K1 (0.35) | MAP4K1 | |
| SCHEMBL24310347 | 0.79 | GPR39 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |