Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 7/20 | 0.34 |
| ▸ | CA2 | P00918 | 7/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708085 | 0.88 | POLB (0.40) | MAPTPKMCA1CA2CA9 | |
| SCHEMBL3174224 | 0.86 | TAS1R3 (0.35) | MAPTPKMCA1CA2CA9 | |
| SCHEMBL8022828 | 0.85 | TP53 (0.39) | TAS1R3TAS1R1TP53CYP3A4KDM4E | |
| SCHEMBL8703906 | 0.82 | POLB (0.39) | MAPTPKMCA1CA2CA9 | |
| SCHEMBL1722174 | 0.80 | ALDH1A1 (0.39) | MAPTTAS1R3TAS1R1TP53CYP3A4 | |
| SCHEMBL14382020 | 0.79 | ATM (0.42) | MAPTPKMTAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL2687043 | 0.79 | TAS1R3 (0.36) | CA1CA2CA9CA12TAS1R3 | |
| SCHEMBL3765069 | 0.78 | ALDH1A1 (0.34) | MAPTTAS1R3TAS1R1TLR4TP53 | |
| SCHEMBL1476733 | 0.78 | ALDH1A1 (0.36) | CA1CA2CA9CA12TAS1R3 | |
| SCHEMBL8704584 | 0.76 | POLB (0.38) | TAS1R3TAS1R1NPSR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| EP-2186791-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186791-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186805-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2184275-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
| EP-2184275-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-1989162-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007096058-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007096058-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PIKFYVE | MAPT 4068/4885PKM 4/4885CA1 1054/4885 |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PKM | MAPT 4448/4885PKM 3/4885CA1 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.