SCHEMBL2431865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27596557	0.89	ITGB1 (0.52)	ITGB1ITGA4LMNAMAOBHDAC1
	SCHEMBL14591768	0.89	ITGB1 (0.53)	ITGB1ITGA4LMNAMAOBHDAC1
	SCHEMBL70951	0.88	RAB9A (0.52)	ITGB1ITGA4LMNAMAOBMAPT
	SCHEMBL2433554	0.87	ITGB1 (0.58)	ITGB1ITGA4LMNAHDAC1HDAC6
	SCHEMBL2433768	0.87	LMNA (0.50)	ITGB1ITGA4LMNAHDAC1MAPT
	SCHEMBL12327956	0.87	ITGB1 (0.51)	ITGB1ITGA4LMNAMAOBHDAC1
	SCHEMBL2429129	0.87	ITGB1 (0.55)	ITGB1ITGA4LMNAMAOBHDAC1
	SCHEMBL2435675	0.86	ITGB1 (0.45)	ITGB1ITGA4HDAC1HDAC6POLB
	SCHEMBL2433520	0.86	HDAC1 (0.52)	ITGB1ITGA4LMNAHDAC1HDAC6
	SCHEMBL72352	0.85	POLB (0.61)	ITGB1ITGA4LMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.