Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF1 | Q13422 | 3/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24321361 | 0.85 | IKZF2 (0.37) | IKZF1IKZF2 | |
| SCHEMBL25626791 | 0.84 | DRD2 (0.42) | IKZF1IKZF2 | |
| SCHEMBL24790789 | 0.79 | IKZF2 (0.35) | IKZF1IKZF2 | |
| SCHEMBL25619160 | 0.76 | THRB (0.34) | IKZF1IKZF2 | |
| SCHEMBL24891481 | 0.75 | NAMPT (0.36) | — | |
| SCHEMBL24320751 | 0.73 | IKZF1 (0.72) | IKZF1IKZF2 | |
| Hydrochloric Acid SCHEMBL29583984 | 0.72 | IKZF1 (0.71) | IKZF1IKZF2 | |
| SCHEMBL24891345 | 0.72 | THRB (0.34) | — | |
| SCHEMBL26491771 | 0.71 | MOK (0.50) | — | |
| SCHEMBL24790237 | 0.71 | HRH3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081976-A1 | PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |