Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24321280 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTTLSSKDM4E | |
| SCHEMBL24321065 | 0.81 | MEN1 (0.45) | ALDH1A1LMNA | |
| SCHEMBL24307312 | 0.74 | LMNA (0.59) | ALDH1A1KDM4EHRH3LMNA | |
| SCHEMBL24321613 | 0.74 | HSD11B1 (0.53) | ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL24321063 | 0.73 | HTR1A (0.56) | ALDH1A1SMN1; SMN2HTTKDM4EPOLB | |
| SCHEMBL3920370 | 0.69 | LMNA (0.55) | ALDH1A1SMN1; SMN2HTTKDM4EPOLB | |
| SCHEMBL27399979 | 0.68 | NCF1 (0.48) | ALDH1A1SMN1; SMN2HTTKDM4EPOLB | |
| SCHEMBL2133889 | 0.68 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HTTKDM4EPOLB | |
| SCHEMBL17057244 | 0.68 | KMT2A (0.45) | ALDH1A1SMN1; SMN2HTTKDM4EATM | |
| SCHEMBL3917811 | 0.67 | POLB (0.49) | ALDH1A1SMN1; SMN2HTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078414-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |