Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20075898 | 0.83 | ALDH1A1 (0.52) | NCF1POLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20323922 | 0.73 | ALDH1A1 (0.51) | POLBSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL18551215 | 0.73 | MAPT (0.46) | NCF1POLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21026182 | 0.71 | ME2 (0.49) | POLBSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL30230328 | 0.71 | MAPT (0.49) | NCF1POLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24321060 | 0.68 | ALDH1A1 (0.46) | POLBSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL3920370 | 0.68 | LMNA (0.55) | POLBSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL8472994 | 0.68 | LMNA (0.60) | POLBSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL27399980 | 0.68 | NCF1 (0.55) | NCF1HRH3 | |
| SCHEMBL14220995 | 0.68 | NCF1 (0.73) | NCF1ALDH1A1KDM4EHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108009-A1 | DYRK/CLK PROTACS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-05-23 | — | — | WO | disclosed |