Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | RGS4 | P49798 | 3/20 | 0.47 |
| ▸ | RGS8 | P57771 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | CD74 | P04233 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327517 | 0.89 | RGS4 (0.57) | C5AR1RGS4RGS8HPGDKMT2A | |
| SCHEMBL24327521 | 0.87 | RGS4 (0.55) | C5AR1RGS4RGS8HPGDKMT2A | |
| SCHEMBL24327924 | 0.85 | PGR (0.49) | RGS4RGS8HPGDKMT2AKDM4E | |
| SCHEMBL24327916 | 0.83 | RGS4 (0.44) | RGS4RGS8POLBHPGDKMT2A | |
| SCHEMBL24327426 | 0.83 | P2RX3 (0.44) | RGS4RGS8HPGDTLR7TSHR | |
| SCHEMBL24328815 | 0.80 | RGS4 (0.50) | RGS4RGS8POLBHPGDKMT2A | |
| SCHEMBL24327525 | 0.78 | ALDH1A1 (0.43) | RGS4RGS8HPGDKMT2AMEN1 | |
| SCHEMBL24327915 | 0.78 | NOX4 (0.53) | RGS4RGS8POLBKMT2AMEN1 | |
| SCHEMBL24327518 | 0.78 | KMT2A (0.44) | RGS4RGS8POLBKMT2AMEN1 | |
| SCHEMBL24327523 | 0.74 | MAPT (0.42) | RGS4RGS8POLBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |