Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.39 |
| ▸ | MERTK | Q12866 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328692 | 0.87 | EPHB4 (0.40) | LMNASMN1; SMN2EPHB4TEKKCNH2 | |
| SCHEMBL29498914 | 0.77 | EPHB4 (0.46) | EPHB4TEKKCNH2CCNKCCNA2 | |
| SCHEMBL24328691 | 0.77 | EPHB4 (0.46) | EPHB4TEKKCNH2CCNKCCNA2 | |
| SCHEMBL29601464 | 0.71 | KDR (0.44) | CDK2AURKAAURKB | |
| SCHEMBL24327773 | 0.71 | KCNH2 (0.55) | EPHB4TEKKCNH2 | |
| SCHEMBL24327329 | 0.70 | EPHB4 (0.42) | AXLGABBR2GABBR1TYRO3MERTK | |
| SCHEMBL28724019 | 0.64 | FGFR3 (0.51) | SMN1; SMN2KCNH2CDK2LRRK2AURKA | |
| SCHEMBL24327401 | 0.64 | LRRK2 (0.45) | AXLEPHB4TEKCCNA2CDK2 | |
| SCHEMBL24539466 | 0.63 | MAPK1 (0.41) | SMN1; SMN2AXLEPHB4TEKCCNA2 | |
| SCHEMBL24327324 | 0.63 | FGFR3 (0.50) | KCNH2CDK2AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |