Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469661 | 0.84 | RXFP1 (0.33) | PDE2A | |
| SCHEMBL24333399 | 0.80 | CCR1 (0.33) | — | |
| SCHEMBL24334224 | 0.78 | NFE2L2 (0.35) | — | |
| SCHEMBL24334421 | 0.77 | FABP1 (0.36) | — | |
| SCHEMBL24334394 | 0.75 | PGAM1 (0.33) | — | |
| SCHEMBL24333377 | 0.73 | LMNA (0.34) | — | |
| SCHEMBL24334313 | 0.72 | — | — | |
| SCHEMBL24333964 | 0.72 | HTR6 (0.33) | — | |
| SCHEMBL24334406 | 0.72 | PTGDR (0.34) | — | |
| SCHEMBL24333639 | 0.72 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |