Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469683 | 0.84 | MAPT (0.32) | CCR1COMTHTR3A | |
| SCHEMBL24334224 | 0.82 | NFE2L2 (0.35) | — | |
| SCHEMBL24334303 | 0.80 | PDE2A (0.30) | — | |
| SCHEMBL24333964 | 0.78 | HTR6 (0.33) | — | |
| SCHEMBL24334421 | 0.76 | FABP1 (0.36) | COMT | |
| SCHEMBL24333720 | 0.74 | SLC40A1 (0.35) | — | |
| SCHEMBL24333658 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL24333400 | 0.73 | MAPT (0.32) | CCR1HTR3A | |
| SCHEMBL24333377 | 0.73 | LMNA (0.34) | — | |
| SCHEMBL24333639 | 0.73 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |