SCHEMBL2433628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2428940	0.88	CNR1 (0.37)	HTR2CHTR2BSLC6A4HTR6CNR1
	SCHEMBL2434676	0.85	MAPT (0.37)	PDE4BMAPTKMT2A
	SCHEMBL2431843	0.82	PDE4B (0.38)	PDE4BCYP1A2CYP3A4MAPTALOX15
	SCHEMBL2523334	0.79	PDE4A (0.41)	PDE4BCNR1MEN1TP53CYP3A4
	SCHEMBL15198840	0.77	TSHR (0.39)	PDE4BSLC6A4HTR6KMT2A
	SCHEMBL1136173	0.76	ALDH1A1 (0.43)	TP53CYP1A2MAPTCYP2C19
	SCHEMBL1136053	0.74	ALDH1A1 (0.42)	HTR2CHTR2BMAPTKMT2A
	SCHEMBL2437380	0.73	FFAR1 (0.39)	PDE4BMEN1KMT2APRKAB2PRKAG1
	SCHEMBL1136059	0.72	MET (0.40)	PDE4B
	SCHEMBL2433373	0.71	TDP1 (0.38)	PDE4BCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.