SCHEMBL2437380

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2433373	0.85	TDP1 (0.38)	BRD4PDE4APDE4BPDE4CPDE4D
	SCHEMBL1136059	0.80	MET (0.40)	BRD4PDE4APDE4BPDE4CPDE4D
	SCHEMBL1135964	0.78	MAOB (0.39)	BRDTPDE4DPDGFRBMETKDR
	SCHEMBL2523334	0.77	PDE4A (0.41)	BRD4MEN1KMT2APDE4APDE4B
	SCHEMBL1136191	0.77	MET (0.38)	FFAR1PPARDBRD4FFAR4MET
	SCHEMBL2430551	0.76	BRDT (0.39)	BRDTPDE4B
	SCHEMBL2433050	0.75	TDP1 (0.37)	BRD4ELANEPDE4APDE4BPDE4C
	SCHEMBL2434890	0.74	ADORA3 (0.38)	BRDTMEN1KMT2APDE4B
	SCHEMBL1136159	0.74	MAOB (0.36)	FFAR1PPARDBRDTPDGFRBMET
	SCHEMBL2433628	0.73	PDE4B (0.38)	MEN1KMT2APDE4BPRKAB2PRKAG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.