SCHEMBL2523334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2433373	0.91	TDP1 (0.38)	PDE4APDE4BPDE4CPDE4DTDP1
	SCHEMBL1136059	0.90	MET (0.40)	PDE4APDE4BPDE4CPDE4DTDP1
	SCHEMBL1136191	0.86	MET (0.38)	TDP1METIDO1BRD4KDR
	SCHEMBL2433050	0.85	TDP1 (0.37)	PDE4APDE4BPDE4CPDE4DTDP1
	SCHEMBL2430280	0.85	ADORA3 (0.42)	CNR1CNR2IDO1ALDH1A1CYP3A4
	SCHEMBL2430302	0.84	ALDH1A1 (0.46)	CNR1CNR2IDO1ALDH1A1CYP3A4
	SCHEMBL2433158	0.83	ALDH1A1 (0.39)	IDO1ALDH1A1CYP3A4KDM4ENPC1
	SCHEMBL2433750	0.82	XDH (0.41)	METIDO1ALDH1A1CYP3A4KDM4E
	SCHEMBL2432859	0.81	ADORA3 (0.43)	TDP1METIDO1ALDH1A1CYP3A4
	SCHEMBL2430197	0.81	PDE4A (0.40)	PDE4APDE4BPDE4CPDE4DCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.