Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731616 | 0.81 | TDP1 (0.42) | L3MBTL1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL3889500 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL229353 | 0.76 | KDM4C (0.53) | L3MBTL1ALDH1A1KDM4EGAATDP1 | |
| SCHEMBL30316868 | 0.76 | KDM4C (0.53) | L3MBTL1ALDH1A1KDM4EGAATDP1 | |
| SCHEMBL1135627 | 0.75 | SIRT3 (0.60) | L3MBTL1ALDH1A1KDM4ETDP1SIRT3 | |
| SCHEMBL2579028 | 0.75 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL30849093 | 0.75 | TDP1 (0.46) | L3MBTL1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL16414200 | 0.75 | TDP1 (0.46) | L3MBTL1ALDH1A1KDM4EGAAGLA | |
| SCHEMBL24288684 | 0.72 | CES2 (0.58) | ALDH1A1GAATDP1KMT2AMEN1 | |
| SCHEMBL25236818 | 0.69 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183236-B1 | METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER | MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WSS (DE) | 2022-04-20 | — | — | EP | disclosed |