Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 13/20 | 0.60 |
| ▸ | HTR1A | P08908 | 12/20 | 0.56 |
| ▸ | HTR1D | P28221 | 11/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259141 | 0.87 | HTR2A (0.53) | HTR1BHTR1AHTR1DMAPTMAPK1 | |
| SCHEMBL12247689 | 0.80 | HTR1B (0.60) | HTR1BHTR1AHTR1DMAPTMAPK1 | |
| SCHEMBL12180277 | 0.80 | HTR2B (0.70) | HTR1BHTR1AHTR1DMAPTHTR2A | |
| SCHEMBL7085697 | 0.79 | TRPM8 (0.60) | HTR1BHTR1AHTR1DMAPTKDM4E | |
| SCHEMBL23269931 | 0.79 | HTR1B (0.71) | HTR1BHTR1AHTR1DMAPTMAPK1 | |
| SCHEMBL7056044 | 0.78 | MTNR1A (0.61) | HTR1BHTR1AHTR1DMAPTMAPK1 | |
| SCHEMBL8321115 | 0.78 | HTR1B (0.93) | HTR1BHTR1AHTR1DMAPTMAPK1 | |
| SCHEMBL14961026 | 0.78 | HTR1B (0.78) | HTR1BHTR1AHTR1DMAPTMAPK1 | |
| SCHEMBL5469807 | 0.77 | HTR1B (0.67) | HTR1BHTR1AHTR1DMAPTMAPK1 | |
| SCHEMBL19465380 | 0.76 | HTR2A (0.51) | HTR1AHTR2AKDM4EHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | HTR1B 4873/4885HTR1A 4870/4885HTR1D 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.