Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372556 | 0.94 | LMNA (0.49) | FFAR1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24372731 | 0.94 | MGLL (0.46) | FFAR1 | |
| SCHEMBL24372552 | 0.88 | LMNA (0.46) | FFAR1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4457866 | 0.87 | TDP1 (0.56) | FFAR1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24372729 | 0.80 | ALDH1A1 (0.50) | LMNATDP1ALDH1A1MEN1POLB | |
| SCHEMBL24372557 | 0.79 | MGLL (0.44) | FFAR1LMNATDP1PLA2G4B | |
| SCHEMBL24372734 | 0.79 | LMNA (0.53) | FFAR1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL162267 | 0.77 | LMNA (0.51) | FFAR1LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14063399 | 0.77 | LMNA (0.51) | FFAR1LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24372593 | 0.76 | SIGMAR1 (0.47) | TDP1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | FFAR1 3918/4885LMNA 1891/4885TDP1 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.