SCHEMBL24390287

SCHEMBL24390287

CNCCCC[C@H](NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)C)C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 5/20 0.38
▸ ITGB1 P05556 1/20 0.35
▸ ITGA5 P08648 1/20 0.35
▸ ROCK2 O75116 1/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.33
▸ KLKB1 P03952 2/20 0.32
▸ CTSL P07711 1/20 0.32
▸ ALB P02768 1/20 0.32
▸ SIRT2 Q8IXJ6 6/20 0.32
▸ SIRT1 Q96EB6 5/20 0.32
▸ SIRT3 Q9NTG7 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24401393 0.91 FURIN (0.36) FURINROCK2SIRT5KLKB1CTSL
SCHEMBL29528370 0.89 FURIN (0.40) FURINROCK2CTSL
SCHEMBL29623561 0.89 FURIN (0.40) FURINROCK2CTSL
SCHEMBL30483106 0.88 FURIN (0.40) FURINROCK2KLKB1CTSL
SCHEMBL26015579 0.87 ITGB1 (0.43) ITGB1ITGA5
SCHEMBL25383060 0.86 FURIN (0.37) FURINSIRT5ALBSIRT2SIRT1
SCHEMBL29048536 0.86 FURIN (0.37) FURINSIRT5ALBSIRT2SIRT1
SCHEMBL26015691 0.85 FURIN (0.37) FURINITGB1ITGA5SIRT5SIRT2
SCHEMBL23071953 0.85 CASP1 (0.35) FURIN
SCHEMBL22690077 0.85 CASP1 (0.35) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744897-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof ELUCIDA ONCOLOGY, INC. (US) 2023-09-05 — — US disclosed
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed
WO-2022093794-A1 METHODS OF FUNCTIONALIZING NANOPARTICLES ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP FURIN 2087/4885ITGB1 2939/4885ITGA5 3119/4885
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR FURIN 2202/4885ITGB1 1981/4885ITGA5 1379/4885
US-11744897-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof FOLR1, FOLR2, DHFR FURIN 2202/4885ITGB1 1981/4885ITGA5 1379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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