Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12543528 | 0.91 | HDAC1 (0.51) | ALDH1A1L3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL1963123 | 0.90 | HDAC1 (0.43) | ALDH1A1L3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL17761442 | 0.80 | HDAC1 (0.54) | ALDH1A1L3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL30801697 | 0.79 | HDAC1 (0.45) | ALDH1A1L3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL22770534 | 0.78 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL2262766 | 0.77 | CYP3A4 (0.52) | ALDH1A1L3MBTL1HDAC6HDAC1KDM1A | |
| SCHEMBL5423537 | 0.76 | HDAC1 (0.44) | ALDH1A1L3MBTL1HDAC6HDAC1HDAC8 | |
| SCHEMBL29967631 | 0.76 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1HDAC6HDAC1KDM1A | |
| SCHEMBL1963140 | 0.75 | AADAT (0.49) | ALDH1A1L3MBTL1GAACYP3A4CYP2C19 | |
| SCHEMBL8294396 | 0.75 | MMP1 (0.47) | ALDH1A1L3MBTL1HDAC6HDAC1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022094271-A1 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |