Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24401094 | 0.81 | LOXL2 (0.41) | MAOBSCN9A | |
| SCHEMBL922221 | 0.79 | MAOB (0.69) | MAOBTAAR1IDO1LTA4HST14 | |
| SCHEMBL4374065 | 0.78 | THRB (0.47) | MAOBLTA4HKCNH2SCN9ASCN5A | |
| Hydrochloric Acid SCHEMBL4373482 | 0.78 | MAOB (0.72) | MAOBTAAR1IDO1LTA4HST14 | |
| SCHEMBL9106039 | 0.75 | SMN1; SMN2 (0.42) | MAOBSCN9ALMNAMAPT | |
| SCHEMBL4371705 | 0.75 | MAOB (0.54) | MAOBSCN9AALDH1A1LMNAMAPT | |
| SCHEMBL9106047 | 0.74 | LMNA (0.42) | MAOBSCN9AALDH1A1LMNAMAPT | |
| SCHEMBL4370646 | 0.74 | KIF11 (0.47) | MAOBLTA4HKCNH2SCN9ASCN5A | |
| SCHEMBL17136438 | 0.74 | LOXL2 (0.66) | MAOB | |
| SCHEMBL4371434 | 0.73 | SRD5A2 (0.49) | ALDH1A1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |