Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24406754 | 0.83 | LMNA (0.46) | KDM4EL3MBTL1HSD17B10GAALMNA | |
| SCHEMBL24409726 | 0.83 | L3MBTL1 (0.52) | MAPK1HDAC6KDM4EFFAR4NPC1 | |
| SCHEMBL24409736 | 0.79 | FFAR4 (0.39) | MAPK1HDAC6KDM4EFFAR4NPC1 | |
| SCHEMBL24409961 | 0.77 | TBXAS1 (0.45) | MAPK1HSD11B1KDM4ERAB9ARXFP1 | |
| SCHEMBL23447091 | 0.76 | HDAC6 (0.38) | MAPK1HDAC6KDM4EFFAR4NPC1 | |
| SCHEMBL23447089 | 0.74 | RXRA (0.41) | MAPK1HDAC6KDM4EL3MBTL1HSD17B10 | |
| SCHEMBL26938548 | 0.73 | PKM (0.40) | HSD11B1KDM4EL3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL24409848 | 0.73 | FFAR1 (0.40) | MAPK1HDAC6KDM4EFFAR4L3MBTL1 | |
| SCHEMBL24409727 | 0.73 | ALDH1A1 (0.39) | MAPK1HDAC6KDM4EL3MBTL1GAA | |
| SCHEMBL241757 | 0.71 | ALDH1A1 (0.48) | MAPK1HDAC6LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096449-A1 | [(1,5-DIHETEROARYL-1H-1,2,4-TRIAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | disclosed |