Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 11/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21755744 | 0.81 | POLB (0.52) | TP53POLBMAPTLMNARXFP1 | |
| SCHEMBL24098714 | 0.80 | MEN1 (0.59) | MEN1KMT2ATP53POLBMAPT | |
| Hydrochloric Acid SCHEMBL30381282 | 0.79 | MEN1 (0.58) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL9110763 | 0.77 | MEN1 (0.56) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL9110471 | 0.77 | MEN1 (0.56) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL24098896 | 0.74 | MEN1 (0.68) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL15043470 | 0.73 | GABRA5 (0.58) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL18057328 | 0.72 | KMT2A (1.00) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL24098928 | 0.70 | MAPT (0.68) | TP53POLBMAPTLMNARXFP1 | |
| SCHEMBL16098656 | 0.70 | FABP4 (0.53) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144845-A1 | SUBSTITUTED PYRROLO[1,2-a]QUINOXALIN-4(5H)-ONES AS CX3CR1 ANTAGONISTS | UNIV DREXEL (US) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144845-A1 | SUBSTITUTED PYRROLO[1,2-a]QUINOXALIN-4(5H)-ONES AS CX3CR1 ANTAGONISTS | CX3CR1, CCR5, CCL2 | MEN1 3473/4885KMT2A 3843/4885TP53 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.