SCHEMBL24445490

SCHEMBL24445490

Cc1ccc(N(c2ccc(C)c(C)c2)c2ccccc2COC(=O)C(CC(C)(C)C)C(C)(C)C)cc1C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.33
▸ MAPK1 P28482 2/20 0.31
▸ USP2 O75604 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ SIRT5 Q9NXA8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24445580 0.88 ALDH1A1 (0.34) LMNAMEN1ALDH1A1KMT2A
SCHEMBL24405961 0.82 SMN1; SMN2 (0.36) LMNAMAPK1MEN1ALDH1A1KMT2A
SCHEMBL22639354 0.76 THRB (0.35) LMNAMAPK1USP2MEN1ALDH1A1
SCHEMBL22639357 0.70 S1PR1 (0.42) LMNAMEN1ALDH1A1KMT2A
SCHEMBL24445503 0.70 ALDH1A1 (0.38) LMNAMEN1ALDH1A1KMT2A
SCHEMBL10069694 0.69 ALDH1A1 (0.51) LMNAMAPK1ALDH1A1KMT2A
SCHEMBL10077943 0.67 EGFR (0.36) —
SCHEMBL10077942 0.67 CYBB (0.34) USP2MEN1KMT2A
SCHEMBL24859837 0.66 MMP1 (0.34) LMNAMEN1ALDH1A1KMT2A
SCHEMBL25445790 0.66 POLB (0.36) MAPK1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3575879-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE-FORMING APPARATUS CANON KK (JP) 2022-05-25 — — EP disclosed
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