Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24612546 | 0.87 | ICMT (0.45) | HPGDSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL24445994 | 0.86 | TAAR1 (0.44) | — | |
| SCHEMBL1428025 | 0.84 | LMNA (0.62) | HPGDSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL4228874 | 0.81 | CYP4F2 (0.50) | HPGDSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL3357146 | 0.78 | GAA (0.55) | HPGDSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL27594421 | 0.77 | HPGD (0.55) | HPGDSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL3358287 | 0.76 | CYP4F2 (0.59) | HPGDSMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL24612566 | 0.73 | MMP12 (0.40) | LMNAHTTALDH1A1 | |
| SCHEMBL7236732 | 0.73 | FFAR1 (0.61) | SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6801321 | 0.73 | LMNA (0.56) | HPGDSMN1; SMN2NPC1PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026828-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-07-13 | — | — | EP | disclosed |
| EP-4001414-A1 | NONHUMAN ANIMAL AND USE FOR SAME | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-05-25 | — | — | EP | disclosed |