SCHEMBL2444784

SCHEMBL2444784

CC(C)(O)C(=O)c1ccc(OCCOCC2CO2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
ALDH1A1 P00352 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TP53 P04637 2/20 0.46
HPGD P15428 2/20 0.46
TSHR P16473 2/20 0.46
CYP1A2 P05177 1/20 0.46
PPARG P37231 1/20 0.46
HIF1A Q16665 1/20 0.46
PKM P14618 3/20 0.40
GAA P10253 2/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
RARB P10826 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
THRA P10827 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2471221 0.88 ALDH1A1 (0.59) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL3975884 0.88 ALDH1A1 (0.44) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL11967035 0.83 L3MBTL1 (0.55) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL11967034 0.83 L3MBTL1 (0.55) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL8678393 0.81 MAPT (0.45) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL17921585 0.81 MAPT (0.50) MAPTALDH1A1PKMGAALMNA
SCHEMBL9325190 0.80 TDP1 (0.55) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL9808683 0.79 MAPT (0.47) MAPTALDH1A1TP53TSHRPKM
SCHEMBL9947183 0.79 THRA (0.56) MAPTTP53TSHRPKMGAA
SCHEMBL20019518 0.79 GAA (0.56) MAPTALDH1A1PKMGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281941-B1 Coreactive photoinitiators CIBA GEIGY AG (CH) 1993-12-08 EP claimed
EP-0281941-A2 Coreactive photoinitiators CIBA-GEIGY AG (CH) 1988-09-14 EP claimed
JP-10175908-A None JP disclosed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US disclosed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US disclosed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US disclosed
EP-2585494-B1 HYDROPHILIC GELS FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST AS (DK) 2017-08-09 EP disclosed
EP-2585494-B1 HYDROPHILIC GELS FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST AS (DK) 2017-08-09 EP disclosed
US-20160002400-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2016-01-07 US disclosed
US-20160002400-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2016-01-07 US disclosed
US-20160002400-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2016-01-07 US disclosed
US-20090104464-A1 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces IGM GROUP B.V. (NL) 2009-04-23 US disclosed
US-20090104464-A1 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces IGM GROUP B.V. (NL) 2009-04-23 US disclosed
US-20090104464-A1 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces IGM GROUP B.V. (NL) 2009-04-23 US disclosed
WO-2009050116-A2 ADHESION PROMOTING PHOTOINITIATORS FOR UV CURED COATINGS OVER METAL SURFACES BASF SE (DE) 2009-04-23 WO disclosed
WO-2009050116-A2 ADHESION PROMOTING PHOTOINITIATORS FOR UV CURED COATINGS OVER METAL SURFACES BASF SE (DE) 2009-04-23 WO disclosed
JP-H10175908-A PHOTOPOLYMERIZATION INITIATOR CIBA SPECIALTY CHEM HOLDING INC 1998-06-30 JP disclosed
US-5532112-A PHOTOPOLYMERIZATION CIBA-GEIGY CORPORATION (US) 1996-07-02 US disclosed
EP-0281941-B1 Coreactive photoinitiators CIBA GEIGY AG (CH) 1993-12-08 EP disclosed
EP-0281941-A2 Coreactive photoinitiators CIBA-GEIGY AG (CH) 1988-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104464-A1 Adhesion promoting photoinitiators for UV cured coatings over metal surfaces CDH1, PCNA, VCAM1 MAPT 361/4885ALDH1A1 302/4885MEN1 1093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.