SCHEMBL244516

SCHEMBL244516

C=C(C)C(=O)OC(OC(=O)CCCCCCC/C=C\CCCCCCCC)C(C)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.50
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49
DGKA P23743 1/20 0.48
LPAR1 Q92633 6/20 0.47
DAGLA Q9Y4D2 1/20 0.47
LMNA P02545 2/20 0.47
ENPP2 Q13822 2/20 0.46
LPAR4 Q99677 2/20 0.46
LPAR5 Q9H1C0 2/20 0.46
LPAR2 Q9HBW0 2/20 0.46
LPAR3 Q9UBY5 2/20 0.46
CES2 O00748 1/20 0.46
LPAR6 P43657 1/20 0.46
TRPV1 Q8NER1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245323 0.92 LMNA (0.54) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL245004 0.92 LMNA (0.54) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL245029 0.92 LMNA (0.54) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL242459 0.89 ALDH1A1 (0.52) LMNA
SCHEMBL4975150 0.87 LMNA (0.43) PRKCAPRKCEPRKCQPRKCDLPAR1
SCHEMBL16166698 0.86 PRKCA (0.53) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL17219869 0.80 PRKCA (0.57) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL29040583 0.80 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDDGKA
SCHEMBL4975784 0.79 TSHR (0.41) LMNA
SCHEMBL180886 0.78 FAAH (0.53) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9221738-B2 Method and system for purifying monomers EVONIK RÖHM GMBH (DE) 2015-12-29 US disclosed
US-20120000764-A1 METHOD AND SYSTEM FOR PURIFYING MONOMERS EVONIK DEGUSSA GMBH (DE) 2012-01-05 US disclosed