Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.64 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771734 | 1.00 | LMNA (0.68) | LMNAHTTNPC1RAB9AHSD17B10 | |
| SCHEMBL330371 | 0.83 | TMPRSS4 (0.68) | KCNMA1P2RX1P2RX4P2RX7KDR | |
| SCHEMBL11766410 | 0.81 | NPC1 (0.64) | LMNAHTTNPC1RAB9AHSD17B10 | |
| SCHEMBL31093979 | 0.80 | KCNMA1 (0.71) | LMNAHTTNPC1RAB9ATP53 | |
| SCHEMBL16147455 | 0.80 | KCNMA1 (0.71) | LMNAHTTNPC1RAB9ATP53 | |
| SCHEMBL25680640 | 0.80 | NPC1 (0.70) | LMNAHTTNPC1RAB9AHSD17B10 | |
| SCHEMBL330342 | 0.78 | KDR (0.65) | LMNAHTTNPC1RAB9AKCNMA1 | |
| SCHEMBL20511433 | 0.78 | NPC1 (0.59) | LMNAHTTNPC1RAB9AHSD17B10 | |
| SCHEMBL24460164 | 0.77 | TAS1R3 (0.76) | LMNAHTTNPC1RAB9ATP53 | |
| SCHEMBL13928800 | 0.77 | KCNMA1 (0.72) | RAB9AHSD17B10TP53TSHRKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION | 2024-01-04 | — | — | US | claimed |
| US-20240366540-A1 | MITOFUSIN INHIBITORS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2024-11-07 | — | — | US | disclosed |
| EP-4444284-A1 | MITOFUSIN INHIBITORS AND USES THEREOF | Albert Einstein College of Medicine (US) | 2024-10-16 | — | — | EP | disclosed |
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION | 2024-01-04 | — | — | US | disclosed |
| WO-2023107880-A1 | MITOFUSIN INHIBITORS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107880-A1 | MITOFUSIN INHIBITORS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2022109148-A1 | SMALL MOLECULE INHIBITORS OF SARS-COV-2 INFECTIONS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | ACE2, ACE, TMPRSS2 | LMNA 4211/4885HTT 4703/4885NPC1 478/4885 |
| US-20240366540-A1 | MITOFUSIN INHIBITORS AND USES THEREOF | TFAM, MFN2, MAVS | LMNA 1742/4885HTT 3089/4885NPC1 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.