Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181176 | 0.81 | LMNA (0.44) | LMNA | |
| SCHEMBL3622188 | 0.78 | LMNA (0.41) | LMNA | |
| SCHEMBL3202774 | 0.69 | — | — | |
| SCHEMBL8743203 | 0.67 | LMNA (0.44) | LMNA | |
| SCHEMBL6379416 | 0.65 | ALDH1A1 (0.47) | LMNA | |
| Acrylic Acid SCHEMBL1809604 | 0.65 | LMNA (0.59) | LMNA | |
| SCHEMBL372525 | 0.65 | ALDH1A1 (0.47) | LMNA | |
| SCHEMBL9567032 | 0.65 | ALDH1A1 (0.47) | LMNA | |
| Acrylic Acid SCHEMBL11288299 | 0.63 | LMNA (0.56) | LMNA | |
| Acrylamide SCHEMBL28699720 | 0.63 | ALDH1A1 (0.61) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547688-B1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8623934-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8541483-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20130197176-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130178594-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-8415405-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-04-09 | — | — | US | disclosed |
| EP-2547688-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | Johnson & Johnson Vision Care, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20110237766-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. | 2011-09-29 | — | — | US | disclosed |
| WO-2011116206-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197176-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | CRYAA, MGMT, UACA | LMNA 2848/4885 |
| US-20110237766-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | CRYAA, MGMT, UACA | LMNA 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.