Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244899 | 0.73 | LMNA (0.37) | ALDH1A1POLBSMN1; SMN2HTTKDM4E | |
| SCHEMBL27373488 | 0.71 | SMN1; SMN2 (0.50) | ALDH1A1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1256860 | 0.69 | CA1 (0.43) | ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL6788210 | 0.66 | NR1H2 (0.43) | ALDH1A1NR1H3NR1H2KDM4EMEN1 | |
| SCHEMBL4424149 | 0.66 | KMT2A (0.63) | ALDH1A1POLBNR1H3NR1H2HTT | |
| SCHEMBL30758585 | 0.64 | ALDH1A1 (0.55) | ALDH1A1POLBNR1H3NR1H2RAB9A | |
| SCHEMBL29168848 | 0.64 | ALDH1A1 (0.55) | ALDH1A1POLBNR1H3NR1H2RAB9A | |
| SCHEMBL7071784 | 0.62 | KDM4E (0.40) | SMN1; SMN2KDM4E | |
| SCHEMBL6837995 | 0.62 | LMNA (0.43) | ALDH1A1KDM4E | |
| SCHEMBL14844567 | 0.62 | ALDH1A1 (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284736-B1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3284736-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUtech Ventures (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2537826-B1 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9302990-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2016-04-05 | — | — | US | disclosed |
| EP-2726446-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | Nutech Ventures (US) | 2014-05-07 | — | — | EP | disclosed |
| US-8604213-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2013-12-10 | — | — | US | disclosed |
| US-8377704-B2 | Detection and quantification of anions | NUTECH VENTURES (US) | 2013-02-19 | — | — | US | disclosed |
| WO-2013003734-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2013-01-03 | — | — | WO | disclosed |
| EP-2537826-A1 | Fluorination of aromatic ring systems | Nutech Ventures (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2012-01-05 | — | — | US | disclosed |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-12-22 | — | — | US | disclosed |
| US-20110091982-A1 | Detection and Quantification of Anions | NUTECH VENTURES | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | PFAS, SLC43A1, DDC | ALDH1A1 2774/4885POLB 929/4885NR1H3 4343/4885 |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | PFAS, SLC43A1, DDC | ALDH1A1 2774/4885POLB 929/4885NR1H3 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.