SCHEMBL245046

SCHEMBL245046

C=Cc1ccc([Si](O[SiH](C)C)(O[SiH](C)C)O[SiH](C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
TSHR P16473 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
TRPA1 O75762 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24064756 0.88 ALDH1A1 (0.37) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL5701448 0.78 TP53 (0.44) ALDH1A1TSHRHDAC8TRPA1TDP1
SCHEMBL100085 0.77 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL17248004 0.76
SCHEMBL992478 0.73 ALDH1A1 (0.46) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL20362687 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5701536 0.72 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL431999 0.72 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL28680617 0.72 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL19856497 0.72 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO LTD (JP) 2026-03-19 US disclosed
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER OREAL (FR) 2025-12-18 US disclosed
EP-4626941-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE Dow Toray Co., Ltd. (JP) 2025-10-08 EP disclosed
CN-120129707-A Solid particles of silicone-functional copolymer, method for producing same, and cosmetic containing same 陶氏东丽株式会社 2025-06-10 CN disclosed
WO-2025095111-A1 POLYMER, WATER REPELLENT AGENT, FIBER PRODUCT, AND METHOD FOR PRODUCING FIBER PRODUCT ダイキン工業株式会社 2025-05-08 WO disclosed
WO-2025061338-A1 SOLID COMPOSITION IN POWDER FORM COMPRISING A FILM-FORMING POLYMER IN THE SOLID STATE L'OREAL (FR) 2025-03-27 WO disclosed
WO-2025061352-A1 PROCESS FOR PREPARING A COSMETIC COMPOSITION COMPRISING A PULVERULENT PHASE AND A FILM-FORMING POLYMER SOLUBILIZED IN A VOLATILE SOLVENT; AND PIGMENT FORMULATION. L'OREAL (FR) 2025-03-27 WO disclosed
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER L'OREAL (FR) 2025-02-06 US disclosed
EP-4452193-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER L'OREAL (FR) 2024-10-30 EP disclosed
CN-118382418-A Cosmetic composition comprising polyhydroxyalkanoate copolymer with (unsaturated) hydrocarbon-based chain and silicone polymer 欧莱雅 2024-07-23 CN disclosed
US-6534590-B1 Vinyl monomer, carbosiloxane dendrimer, surfactant, and free radical initiator; waterproof coatings; storage stability DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-03-18 US disclosed
US-6420504-B1 POLYSILOXANES DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-07-16 US disclosed
US-6291021-B1 MATERIAL COMPRISING PENDANT CARBOSILOXANE-DENDRIMER FUNCTIONAL VINYL-TYPE POLYMER COMPRISING CARBOSILOXANE DENDRIMER GROUP AND ACRYLIC RESIN WHICH DOES NOT CONTAIN PENDANT CARBOSILOXANE DENDRIMER STRUCTURE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2001-09-18 US disclosed
US-6238745-B1 APPLYING CARBOSILOXANE POLYMER DOW CORNING TORAY SILICONE CO. LTD. (JP) 2001-05-29 US disclosed
EP-1095953-A2 Silicone-grafted vinyl copolymer emulsion composition Dow Corning Toray Silicone Company, Ltd. (JP) 2001-05-02 EP disclosed
EP-1055674-A1 BRANCHED SILOXANE/SILALKYLENE COPOLYMER, SILICONE-CONTAINING ORGANIC POLYMER, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Silicone Company, Ltd. (JP) 2000-11-29 EP disclosed
EP-1013702-A2 Gas-permeable film Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1013736-A2 Water repellent for treating solids Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-28 EP disclosed
EP-1011033-A2 Carrier, toner and electrophotographic photoreceptor comprising a carbosiloxane dendrimer-functional vinyl type polymer Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-21 EP disclosed
EP-1006165-A2 Coating material Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE FOXM1, FOXK1, TAF1L ALDH1A1 332/4885CHRNB2 4629/4885CHRNB4 4738/4885
US-20250381127-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A(N) (UN)SATURATED HYDROCARBON-BASED CHAIN AND A SILICONE POLYMER H1-0, PARN, FASN ALDH1A1 2361/4885CHRNB2 810/4885CHRNB4 698/4885
US-20250041171-A1 EMULSION COMPOSITIONS CONTAINING CARBOSILOXANE DENDRIMER COMPOUND AND AQUEOUS PHASE FILM FORMER CCNO, CUTA, SQLE ALDH1A1 1418/4885CHRNB2 1234/4885CHRNB4 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.