Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 7/20 | 0.45 |
| ▸ | DRD5 | P21918 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22227194 | 0.79 | SLC9A1 (0.46) | SLC9A1DRD2DRD3SLC6A4 | |
| SCHEMBL24592756 | 0.75 | HTR6 (0.43) | MAOBSMN1; SMN2DRD2DRD3RAB9A | |
| SCHEMBL822777 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2SLC9A1KEAP1TSHRRAB9A | |
| SCHEMBL21982548 | 0.73 | MAOA (0.67) | MAOAMAOBDRD1DRD5DRD2 | |
| SCHEMBL18926478 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2SLC9A1KEAP1TSHRRAB9A | |
| SCHEMBL21042484 | 0.72 | KCNMA1 (0.40) | SMN1; SMN2SLC9A1KEAP1TSHRRAB9A | |
| SCHEMBL12204565 | 0.72 | SMN1; SMN2 (0.62) | SMN1; SMN2SLC9A1KEAP1TSHRRAB9A | |
| SCHEMBL13896382 | 0.71 | HDAC1 (0.49) | DRD1SLC6A4 | |
| SCHEMBL16358826 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2SLC9A1KEAP1TSHRRAB9A | |
| SCHEMBL12204569 | 0.70 | RAB9A (0.56) | SMN1; SMN2SLC9A1KEAP1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122916-A1 | SUBSTITUTED PYRAZOLYL PIPERIDINE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-06-16 | — | — | WO | disclosed |