SCHEMBL6125203

SCHEMBL6125203

NC1=C/C(=N\c2ccc(N)cc2)C(N)=C/C1=N\c1ccc(N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.48
▸ TDP1 Q9NUW8 6/20 0.48
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ RAB9A P51151 3/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ NPC1 O15118 2/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ CA12 O43570 3/20 0.39
▸ CA2 P00918 3/20 0.39
▸ CA9 Q16790 3/20 0.39
▸ NOS3 P29474 1/20 0.38
▸ NOS1 P29475 1/20 0.38
▸ NOS2 P35228 1/20 0.38
▸ APP P05067 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12333885 0.88 MAPT (0.38) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL24443824 0.79 PABPC1 (0.44) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL24514478 0.79 PABPC1 (0.37) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL22699857 0.79 MAPT (0.34) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL24443643 0.79 PABPC1 (0.37) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL15037459 0.78 TDP1 (0.39) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL15687380 0.78 MAPT (0.37) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL10782928 0.75 PABPC1 (0.41) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL15039505 0.74 DNM1 (0.41) MAPTTDP1MEN1KMT2ARAB9A
SCHEMBL20288340 0.74 MAPT (0.34) MAPTTDP1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029428-A Nanoenzyme-based lateral flow chromatography and device 斯里·奇特拉·蒂鲁纳尔医学科学与技术研究所 2026-05-12 — — CN disclosed
WO-2025041169-A1 A NANOZYME BASED LATERAL FLOW ASSAY AND DEVICE SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY (IN) 2025-02-27 — — WO disclosed
US-20210205193-A1 TREATMENT COMPOSITION FOR DYEING JOO, SEONG CHEOL (KR) 2021-07-08 — — US disclosed
EP-3111915-B1 CATALYSED DYE SYSTEMS UNIV LEEDS INNOVATIONS LTD (GB) 2017-10-04 — — EP disclosed
EP-3111915-A1 CATALYSED DYE SYSTEMS UNIVERSITY OF LEEDS (GB) 2017-01-04 — — EP disclosed
EP-2448545-B1 CATALYSED DYE SYSTEMS UNIV LEEDS (GB) 2016-09-07 — — EP disclosed
US-8535391-B2 Catalysed dye systems UNIVERSITY OF LEEDS (GB) 2013-09-17 — — US disclosed
US-8535391-B2 Catalysed dye systems UNIVERSITY OF LEEDS (GB) 2013-09-17 — — US disclosed
US-20120110751-A1 Catalysed Dye Systems UNIVERSITY OF LEEDS (GB) 2012-05-10 — — US disclosed
US-20120110751-A1 Catalysed Dye Systems UNIVERSITY OF LEEDS (GB) 2012-05-10 — — US disclosed
WO-2011000892-A2 CATALYSED DYE SYSTEMS UNIVERSITY OF LEEDS (GB) 2011-01-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210205193-A1 TREATMENT COMPOSITION FOR DYEING CTH, AADAT, SDHB MAPT 1855/4885TDP1 3226/4885MEN1 1106/4885
US-20120110751-A1 Catalysed Dye Systems FH, TYR, POLR1C MAPT 1134/4885TDP1 1899/4885MEN1 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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