SCHEMBL24517754

SCHEMBL24517754

COC(=O)C1(Cc2ccccc2)CC(CNC(=O)OC(C)(C)C)=NO1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
IDO1 P14902 1/20 0.38
NAMPT P43490 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
KDM4A O75164 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
SYK P43405 1/20 0.37
SIGMAR1 Q99720 2/20 0.37
GRIN2B Q13224 1/20 0.37
ATM Q13315 1/20 0.36
GLS O94925 2/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
NPFFR1 Q9GZQ6 1/20 0.36
NPFFR2 Q9Y5X5 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25397554 0.90 IDO1 (0.41) CA12CA1CA7CA14IDO1
SCHEMBL25400917 0.84 NPC1 (0.45) CA12CA1CA7KMT2AMEN1
SCHEMBL25397863 0.84 CHRM1 (0.41) L3MBTL1CA2
SCHEMBL24517861 0.83 KDM4E (0.35) CA12CA1CA7NAMPTKMT2A
SCHEMBL29846053 0.82 POLB (0.42) KMT2AKDM4AL3MBTL1SYKATM
SCHEMBL24518107 0.82 KDM4E (0.34) CA12CA1CA7NAMPTKMT2A
Hydrochloric Acid SCHEMBL25401859 0.82 TACR1 (0.38) KMT2AMEN1ATM
SCHEMBL25399918 0.82 ALDH1A1 (0.44) KMT2AMEN1L3MBTL1
SCHEMBL29846584 0.81 L3MBTL1 (0.45) KMT2AMEN1L3MBTL1
SCHEMBL29846706 0.81 CTSS (0.43) CA12CA1CA7CA14ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 CA12 381/4885CA1 477/4885CA7 160/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 CA12 1629/4885CA1 1530/4885CA7 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.